Lena was working on Blood from Sam desperately trying to find a Way to Sperate Reign and Sam but so far nothing. " Your in above your Head Luthor " Reign says. " I know exactly what I am doing I am close once I figure out what Causes the change I will stop you. " Lena says. " You wanna know what causes the Change simple I come out when Evil is on the Rise. " Reign says. Lena is unconvinced then Reign puts her Fist through the Cell and starts Choking Lena. Lena taps her Watch sending out a high pitched sound only Few will hear. Reign covers her ears letting Lena go but shoots heat Vision uncontrollably. Meanwhile Kara was writing up a report but hears the Sound and rushes outside changing into her Supergirl outfit and taking flight. Reign breaks out the Cell and charges at Lena until Supergirl flies in and Knocks Reign away. " Stay Down! " Supergirl commands not wanting to hurt Sam. " Oh what a matter where that Killer instinct Supergirl have you gone Soft " Reign taunts and shoots Supergirl with Heat Vision. " Oh I forgot even Your Father found you disappointing. " Reign says grinning evilly. " SHUT UP!!! " Supergirl says Punching Reign then grabbing ahold of her and taking flight. " Kara please don't kill her Sam is Innocent!!!! " Lena says. Supergirl punches Reign knocking her through the Air only to punch her again until she slams Reign outside Catco. " There she is the Mighty Supergirl was that your Best? " Reign ask. Supergirl flies towards Reign who picks up a Car smashing Supergirl with it. " Weak! " Reign says as she picks Supergirl up and slams her. " Your too Soft too pathetic to save this City you never deserved to Survive Kyproton! " Reign says dragging Supergirl and throwing her through Catco. Supergirl crashes into Cat Grant's office. Cat jumps up surprised. Reign walks in. " Cat Grant tell National City that someone truly worthy of being worshipped has arrived. " Reign says. " No. " Supergirl says weakly getting up Slamming into Reign going out the Window. They battle falling punching and Kicking with Reign landing on top. " You once tried to kill me with this Broken Blade you should have. " Reign says as she slams the blade through Supergirl gut. Reign punches Supergirl repeatedly until finally Supergirl went limp not moving not groaning or crying in pain. Reign smirks. " Supergirl is Dead. National City SUPERGIRL IS DEAD!!!!! I WILL FOREVER REIGN!!! " Reign says and flies away. Cat runs outside looking at Supergirl in shock. " Kara. " Cat whispers. DEO Agents arrive only too See Reign gone and Supergirl on the ground lifeless. Alex rushed over hugging Supergirl. " Get up Kara get up. " Alex pleads but nothing. The Agents put Supergirl in a van and Leave. At the DEO they did everything they could but It all Failed. Jonn Jozz looks at them all sadly. " We were too late Supergirl is Dead. " Jonn says.